Cancer Treatment Powder Methotrexate CAS 59-05-2 for Research Use
Product Name: Methotrexate
Methotrexate Properties and Usage:
Chemical Properties It is orange-yellow crystalline powder. It has
a melting point of 185-204 ℃. It is easily soluble in dilute
alkali, acid or alkali metal carbonate solution, and slightly
soluble in dilute hydrochloric acid but almost insoluble in water,
ethanol, chloroform, and ethyl ether.
Production method It is obtained from the cyclization between 2, 4,
5, 6-tetraaminopyrimidine and dibromo propionaldehyde and further
condensation with p-N-Methylaminobenzoylglutamic acid.
Chemical Properties Yellow Crystaline Powder
Usage A Folic acid antagonist. Used as a antineoplastic and
Usage dietary supplement, crosses the blood-brain barrier,
potential activities as anxiolytic and vasodilator
Usage A deuterated folic acid antagonist
Usage Used as a antineoplastic and antirheumatic. A folic Acid
General Description Odorless yellow to orange-brown crystalline
Air & Water Reactions Methotrexate is sensitive to hydrolysis,
oxidation and light. Insoluble in water.
Reactivity Profile Methotrexate decomposes in very acidic or
alkaline conditions. Methotrexate is incompatible with strong
oxidizing agents and strong acids.
Methotrexate Clinical application
It is effective in treating acute leukemia with better efficacy in
pediatric patients. It has a good efficacy in treating
choriocarcinoma and malignant mole. Large dose administration is
effective in treating osteosarcoma, soft tissue sarcoma, lung
cancer, testicular cancer, breast cancer, and ovarian cancer. It is
also effective in treating head and neck cancer, liver cancer and
gastrointestinal cancer. Arterial infusion of this product has goo
efficacy in treating head and neck cancer and liver cancer.
However, it is rarely used for treating psoriasis and psoriasis.
|DMHA / 1,5-Dimethylhexylamine|
|DMBA / 1,3-Dimethylbutylamine|
|DMAA / 1,3-Dimethylpentylamine|
|AMP Citrate / 1,3-dimethylbutylamine citrate|
|DMAE bitartrate / 2-Dimethylaminoethanol bitartrate salt|
|DNP / Sodium 2,4-dinitrophenate|
|gamma-Butyrolactone / GBL|
|4-Acetamidophenol / Paracetamol|
|Tranexamic acid / Amstat|
|Lorcaserin hydrochloride hemihydrate|
|Triamcinolone acetonide acetate|
|Adrenosterone / 11-OXO|
|Apremilast (CC-10004) / Otezla|