USP Purity 99% Isoprenaline Hydrochloride CAS 51-30-9 Resistance to
1. Quick Detail
Name: Isoprenaline hydrochloride
CAS NO.: 51-30-9
Quality standard: enterprise standard
Appearance: white power
1. Bronchial asthma: application to control acute asthma attacks,
usually inhaled administration, the role of fast and strong, but
2. Heart stops together: for the treatment of various reasons,
drowning, electric shock, surgery and other accidents and poisoning
caused by cardiac arrest. Necessary, with epinephrine and
norepinephrine with Wu.
3. Atrioventricular block.
4. Anti-shock: cardiogenic shock, and can be used in septic shock.
On the high central venous pressure, cardiac output is the lower,
should be the basis of their blood volume and then using this
Isoproterenol hydrochloride is a phenethylamine derivative and
selective β-AR adrenergic agonist shown to increase cytosolic cAMP.
Isoproterenol hydrochloride exhibits promotion of glycogen
breakdown and causes bronchodilation and vasorelaxant effects. Also
potentially stimulates relaxation in nitric oxide mediated
endothelium-dependent smooth muscle. Isoproterenol Hydrochloride is
an activator of β2-AR and ERK.
Isoprenaline hydrochloride is also known as isoproterenol
hydrochloride.The active ingredient is the chemical in a medicine
that makes it work. Medicines can have more than one active
ingredient and be available under different brand names. Medicines
include both active ingredients and inactive ingredients.
Isoprenaline hydrochloride (51-30-9) is a sympathomimetic beta
adrenergic agonist medication. It is structurally similar to
epinephrine but acts selectively on beta receptors, activating β1
and β2 receptors equally. Its primary use is for bradycardia or
heart block. By activating β1-receptors on the heart, it induces
positive chronotropic, dromotropic, and inotropic effects.and it
can be used as an inhaled aerosol to treat asthma, although this is
currently a rare treatment.Although it activates all beta
adrenergic receptors, it works in a similar fashion to the more
selective β2-adrenergic agonists by relaxing the airways to
increase airflow.It is also supplied in ampules under the brand
name Isuprel for injection and in sublingual pill form for
treatment of asthma, chronic bronchitis and emphysema.
White or almost white crystalline powder
+75 º to +80 º
Complies by IR
Complies by TLC
Only one principal impurity more than 1.0% and not more than 2.0.
other impurity not more than 1.0%
Loss on drying
Not more than 0.5%
97.0% to 102.0%
6. Side Effects:
Medicines and their possible side effects can affect individual
people in different ways. The following are some of the side
effects that are known to be associated with this medicine. Because
a side effect is stated here, it does not mean that all people
using this medicine will experience that or any side effect.
- Increased blood flow to the skin on the face (facial flushing).
- Shaking, usually of the hands (tremor).
- Awareness of your heartbeat (palpitations).
- Chest pain.
The side effects listed above may not include all of the side
effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with
this medicine, please read the information provided with the
medicine or consult your doctor or pharmacist.
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