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Procaine Base Novocain powder Local Anesthetic Drugs 59-46-1 , topical dental

Procaine Base Novocain powder Local Anesthetic Drugs 59-46-1 , topical dental

Brand Name : nutritionsteroid
Model Number : kobe@chembj.com
Certification : Enterprise Standard
Place of Origin : China
MOQ : 10g
Price : Negotiation
Payment Terms : Bank Transfer, Western Union, MoneyGram, Bitcoin
Supply Ability : 1000kg/Month
Delivery Time : About a week to your door
Packaging Details : Hidden Package
Shipping : FedEx,UPS,DHL,EMS
Payment : Western Union, T/T, Bitcoin
Time : 5-7 days
Assay : 99% min.
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Procaine Base Novocain powder Topical Anaesthetic Medicine Raw Materials 59-46-1


1. Quick Detail:

English name: procaine
English Synonyms: 2-diethylaminoethyl 4-aminobenzoate; novocaine
CAS: 59-46-1
EINECS Number: 200-426-9
Formula: C13H20N2O2
MW: 236.3101
Molecular Structure:
Density: 1.077g / cm3
Boiling point: 373.6 ° C at 760 mmHg
Flash Point: 179.8 ° C
Vapor Pressure: 8.84E-06mmHg at 25 ° C

Assay:99.9%

Appearance:​White crystalline powder


2. Description:

Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of

intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade

name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by

being a sodium channel blocker.Today it is used therapeutically in some countries due to its

sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine was first synthesized in 1905,shortly after amylocaine.[4] It was created by the

German chemist Alfred Einhorn who gave the chemical the trade name Novocaine, from

the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics.

It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of

amylocaine and procaine, cocaine was the most commonly used local anesthetic. Einhorn wished his

new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists,

however, found it very useful. Einhorn was displeased by this and spent many years touring

dental schools to advise them not to use it.

3. Applications:

The primary use for procaine is as a topical anaesthetic.


Procaine is used less frequently today since more effective (and hypoallergenic) alternatives such as

lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine

is a vasodilator, and is often coadministered with epinephrine for the purpose of vasoconstriction.

Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents

the drug from reaching systemic circulation in large amounts, and overall reduces the amount of

anesthetic required.Unlike cocaine, a vasoconstrictor, procaine does not have the euphoric and

addictive qualities that put it at risk for abuse. MDMA manufacturers also use procaine as an additive

at ratios ranging from 1:1 up to 10% MDMA with 90% procaine, which can be life-threatening.


Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase

through hydrolysis intopara-amino benzoic acid (PABA), which is then excreted by the kidneys

into the urine.


Procaine is the primary ingredient in the controversial preparation Gerovital H3 by Ana Aslan

(Romania), which is claimed by its advocates to remedy many effects of aging. The mainstream

medical view is that these claims were seriously studied and discredited in the 1960s.


A 1% procaine injection has been recommended for the treatment of extravasation complications

associated with venipuncture (along with moist heat, ASA, steroids, antibiotics). It has likewise been

recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine),

as it helps relieve pain and vascular spasm.


Procaine is an occasional additive in illicit street drugs, such as cocaine.


COA:

Product NameProcaine Hydrochloride
ColorWhite crystalline powderCas No.51-05-8
StandardUSP34/BP2005
Packing1kgor 5kg/bag, 25kg/drum
Shelf Life24 months
Test ItemsSpecificationTest Results
AppearanceWhite crystals or a white
crystalline powder
Conform
IdentificationABE. It appears positive reaction
Melting point154degree~158degree154degree~157degree
AcidityPH 5.0~6.5PH=5.9
Appearance of solutionClear and colourlessConform
Loss on drying≤0.5%0.07%
Heavy metals≤0.0005%Conform
Related substances≤0.05%Conform
Sulphated ash≤0.1%0.05%
Assay ( on dry basis )99.0-101.0%99.87%
ConclusionConform to BP2005


Local Anesthetic Drugs we supply

Procaine BaseCAS 59-46-1
Lidocaine HClCAS 73-78-9
BenzocaineCAS 94-09-7
Lidocaine HydrochlorideCAS 51-05-8
Xylocaine LidocaineCAS 137-58-6
Tetracaine HClCAS 136-47-0
Propitocaine HydrochlorideCAS 1786-81-8
Aarticaine HydrochlorideCAS 23964-57-0
Procaine HydrochlorideCAS 51-05-8
Tetracaine hydrochlorideCAS 136-47-0
Lidocaine BaseCAS 137-58-6
Dyclonine hydrochlorideCAS 536-43-6
Tetracaine BaseCAS 94-24-6
Dibucaine HydrochlorideCAS 61-12-1
Proparacaine HydrochlorideCAS 5875-06-9
Ropivacaine HydrochlorideCAS 98717-15-8
BupivacaineCAS 2180-92-9
Bupivacaine HydrochlorideCAS 14252-80-3


Product Tags:

anesthetic powder

      

dental anesthesia drugs

      
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