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Aarticaine Hydrochloride CAS 23964-57-0 Aarticaine HCl Local dental local anaesthesia

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Aarticaine Hydrochloride CAS 23964-57-0 Aarticaine HCl Local dental local anaesthesia

Brand Name : nutritionsteroid
Model Number : kobe@chembj.com
Certification : Enterprise Standard
Place of Origin : China
MOQ : 10g
Price : Negotiation
Payment Terms : Bank Transfer, Western Union, MoneyGram, Bitcoin
Supply Ability : 1000kg/Month
Delivery Time : About a week to your door
Packaging Details : Hidden Package
Shipping : FedEx,UPS,DHL,EMS
Payment : Western Union, T/T, Bitcoin
Time : 5-7 days
Assay : 99% min.
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Aarticaine Hydrochloride CAS 23964-57-0 Aarticaine HCl Local Anesthetic raw material

Quick detail:
Alias: Aarticaine Hydrochloride;Articaine HCl; Articaine hydrochloride; Carticaine hydrochloride; HOE 045; HOE 40045; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride; Septanest; Septocaine; UNII-QS9014Q792; Ultracain; Ultracaine;
Assay:99%
CAS: 23964-57-0
MW : 320.839
MF: C18H29ClN2O
EINECS:245-957-7
Grade Standard:USP/BP
Export Markets:Global
Trademark:Aarticaine Hydrochloride
Packing:Different Kinds of Special Packing Methods.
Standard:USP/BP
Origin:China
HS Code:29379000
Production Capacity:800 kg /Month
Local Anesthetic Drug 99% Pain Skiller 23964-57-0 Articaine HCl Aarticaine Hydrochloride Power
Appearance: White crystalline powder


Description:
Articaine hydrochloride , its CAS NO. is 23964-57-0, the synonyms are 2-Thiophenecarboxylic acid,

4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride ; 4-Methyl-3-

(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl ; Articaine HCl ; Methyl

4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride ; Septanest ; Septocaine .
Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.


Structure and metabolism: The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.


Applications:

Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adrenaline.
The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.


Clinical use:

(1) Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient

and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.

(2) In dentistry, articaine is used both for infiltration and block injections, with the block technique

yielding the greatest duration of anesthesia.

(3) In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine

works well.


Product NameAarticaine hydrochloride
SynonymsArticaine hydrochloride [USAN]; 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-
2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride; 4-Methyl-3-
(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl;
Articaine HCl; Articaine hydrochloride; Carticaine hydrochloride; HOE 045;
HOE 40045; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-
thiophenecarboxylate, monohydrochloride; Septanest; Septocaine; UNII-
QS9014Q792; Ultracain; Ultracaine; 2-Thiophenecarboxylic acid, 4-
methyl-3-(2-(propylamino)propionamido)-, methyl ester, monohydrochloride;
Methyl 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-2-thenoate
monohydrochloride; methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-
2-carboxylate hydrochloride (1:1)
Molecular FormulaC 13 H 21 ClN 2 O 3 S
Molecular Weight320.8354
InChIInChI=1/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)
18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H
CAS Registry Number23964-57-0
EINECS245-957-7
Molecular Structure
Boiling point440.6 C at 760 mmHg
Flash point220.3 C
Vapour Pressure5.79E-08mmHg at 25 C
Assay99%
AppearanceWhite crystalline powder


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anesthesia lidocaine

      
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